The acute lymphocytic leukemia (ALL) cell therapy market size was valued at $2.3 billion in 2021. Acute lymphocytic (or lymphoid or lymphoblastic) leukemia (ALL) is a malignancy of the hematopoietic system caused by the abnormal proliferation or differentiation of lymphoid progenitors in the bone marrow. ALL is classified into two main subtypes: T-ALL, which accounts for approximately 20% of total cases, and B-cell ALL (B-ALL). Diagnosis of ALL is dependent on cytogenetics, cell morphology, and immunotyping.
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Acute Lymphocytic Leukemia (ALL) Cell Therapy Market FAQs
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Acute Lymphocytic Leukemia (ALL) Cell Therapy Market Dynamics
Established CAR-T therapies to grow market share via label expansions: Kymriah is expected to move into 1L, and Tecartus is expected to achieve a label for the pediatric patient population. The inability to find a donor for stem cell transplants drives the need for stem cell replacement products such as NiCord and TRGFT-201. The need for “off-the-shelf” products with lower costs and reduced infrastructure requirements drives the development of allogeneic agents.
Pipeline cell therapies will face significant competition from marketed CAR-Ts, which have become established in the ALL setting. The first-line setting is well-served by chemotherapy, with high use of stem cell transplants on relapse. This blocks the entry of cell therapies into more lucrative settings. The lack of established target antigens in T-ALL decreases R&D for this patient population.
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Acute Lymphocytic Leukemia (ALL) Cell Therapy Market Regional Insights
The key regions in the acute lymphocytic leukemia (ALL) cell therapy market are North America, Europe, Middle East, and APAC. North America dominated the market share in 2021. The 15 markets comprise the 8MM and seven countries known to have increased potential for cell therapies given the current drug development landscape including Australia, Belgium, Canada, Denmark, Israel, South Korea, and Switzerland.
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Acute Lymphocytic Leukemia (ALL) Cell Therapy Market – Leading Players
Some of the future players in the acute lymphocytic leukemia cell therapy market are Hebei Senlang Biotechnology, Chongqing Precision Biotech, Sian Wuhan Medical Technology Co Ltd, Novartis AG, iCell Gene Therapeutics LLC, and Wugen Inc among others. Hebei Senlang Biotechnology and Chongqing Precision Biotech are the leading sponsors of cell therapy trials in the ALL market.
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Related Report
1.1. Contents
1.2. Report Scope
3.1. Etiology & Epidemiology
3.2. ALL Treatment Algorithm
4.1. Pipeline Analysis
4.2. Target Analysis and Clinical Benchmarks
5.1. 10-Year Market Analysis with Drivers and Barriers
8.1. Competitive Analysis by Class of Therapy
9.1. Future Players Based on Pipeline Strength
10.1. Cell Therapies Forecast Methodology Overview
10.2. Pricing of Cell Therapies
10.3. Pipeline Launch Assumptions
10.4. Abbreviations
10.5. Methodology
10.6. About the Authors
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