The prevalence of cases of Gastroparesis in the USA is 268 to 339 cases per 100,000 population in the USA was more than twice as common in females than in male individuals, highest in patients aged 58 to 64 years, and lowest in patients aged 18 to 27 years. The prevalence of diabetic gastroparesis ranges between 101 to 105 cases, per 100,000 persons, whereas the prevalence of diabetic gastroparesis among patients with type 1 and type 2 diabetes was 10.4 and 91.0.
Comprehensive insight on patient segmentation based on age, sex, by etiology (T1DM, T2DM, Postsurgical, Drug-induced, Idiopathic, and Other types; Scleroderma, Lupus, Hypothyroidism, Parkinson disease, Cerebral palsy, Multiple sclerosis) and others undefined, severity (Mild, Moderate, and severe), Settings; Refractory cases, Signs & Symptoms, Clinical Manifestations, and has been provided into the epidemiology section of the Gastroparesis and its treatment in the 8 MM countries, covering the United States, EU5 (Germany, Spain, France, Italy, UK), Japan, and China
In terms of pharmacologic therapies, there are few drug candidates/biologicals are in different Phase (Phase I, II & III) stages of development. Key companies are Theravance Biopharma, PTC Therapeutics, CinDome Pharma, Inc., Vanda Pharmaceuticals, GlaxoSmithKline, Bird Rock Bio, Inc., Evoke Pharma, Neurogastrx, Inc., Ironwood Pharmaceuticals, Inc., Takeda, Millennium Phar-maceuticals, Inc., Forest Laboratories, Motus Therapeutics, Inc., and few others. Gastroparesis (GP) has long been in dire need of novel therapies, given the aggressive nature and poor prognosis in the refractory setting. One of the major limitations to drug development is that clinical trials tend to enroll a large number of Gastroparesis severity.
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