Multiple Myeloma Cell Therapy Market Size Worth $25.7 billion in 2021 with the Highest Contribution from North America – GlobalData Plc
The multiple myeloma cell therapy market was valued at $25.7 billion in 2021. Multiple myeloma is a heterogeneous disease, characterized by the aberrant proliferation of plasma cells and subsequent overproduction of monoclonal paraprotein (M protein). a variety of factors, including genetics, environmental and occupational exposure to carcinogens, exposure to radiation, chronic inflammatory state, and infection, are hypothesized to contribute to the causing of this disease. In multiple myeloma, protein levels are routinely used to diagnose and monitor disease progression.
This report includes both cell therapies and established/traditional MM therapies. The 15 markets comprise the 8MM and seven countries known to have increased potential for cell therapies given the current drug development landscape including Australia, South Korea, Belgium, Denmark, Switzerland, Israel, and Canada.
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Multiple Myeloma Cell Therapy Market Dynamics
The multiple myeloma cell therapy market is mainly driven by the approval of autologous CAR-T cell therapies including Abecma and Carvykti. CAR-Ts’ success in MM has fueled R&D investment into this therapy class, with more CAR-Ts in development than all other cell and gene therapy (cell therapy) classes combined.
The approval of the autologous CAR-T cell therapies Abecma and Carvykti sees the CAR-T pipeline mostly constituted of autologous drugs. However, multiple allogeneic CAR-Ts are in the pipeline, with these therapies having an “off-the-shelf” advantage over autologous therapies. Bristol-Myers Squibb’s Abecma is the only marketed cell therapy product in MM as of 2021. However, pipeline cell therapies will face significant competition from marketed CAR-Ts, and are unlikely to gain large market share due to the lack of novel antigens and mechanisms of action (MoAs), as well as comparative clinical trial data. In addition, patients may prefer more convenient therapies which do not require IV administration.
Multiple Myeloma Cell Therapy Market Regional Outlook
The key regions in the MM market are North America, APAC, Europe, and the Middle East. North America had the highest share in 2021. The 15 Markets comprise the 8MM and seven countries known to have increased potential for cell therapies given the current drug development landscape, namely Australia, South Korea, Belgium, Denmark, Switzerland, Israel, Canada.
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Multiple Myeloma Cell Therapy Market – Leading Players
Some of the future players in the MM market are Celgene Corp, Johnson & Johnson, Chongqing Precision Biotech Co Ltd, Shangai Changzheng Hospital, and MediGene AG, among others. Celgene Corp has the highest number of products in ongoing clinical trials and development phases. Leading MM players, such as Johnson & Johnson and Bristol Myers Squibb, are all looking to bolster their positions as market leaders by entering their cell therapies into trials for earlier-stage settings.
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Key Segments Covered in the Report
Multiple Myeloma Cell Therapy Regional Outlook (Value, $Billion, 2021-2031)
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Related Reports
Table of Contents
1.1. Contents
1.2. Report Scope
3.1. MM Etiology & Staging
3.2. Treatment Algorithm
4.1. Marketed Drugs Overview
4.2. Pipeline Analysis
4.3. Target Analysis and Clinical Benchmarks
5.1. 10-Year Market Analysis with Drivers and Barriers
5.2. 10-Year Market Outlook – 15 Markets
8.1. Competitive Analysis by Class of Therapy
9.1. Future Players Based on Pipeline Strength
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